AstraZeneca’s COVID-19 vaccine and the available mRNA COVID-19 vaccines provide equally effective protection against hospitalisation and death from COVID-19 following two doses according to study findings were reported by Expert Review of Vaccines.
The study details indicate that the AstraZeneca COVID-19 vaccine and the BNT162b2 and mRNA1273 mRNA COVID-19 vaccines offer an equivalent degree of protection against hospitalisation (91-93%) and death (91-93%), regardless of age.
The data available at the time of review relates to the Delta SARS-Cov-2 and earlier variants, although emerging data on third dose boosting from the UK Health Security Agency and Brazil indicates similar findings on serious COVID-19 outcomes resulting from the Omicron variant.
Professor Guy Thwaites, Director of the Oxford Clinical Research Unit in Vietnam and one of the study’s authors, said: “COVID-19 vaccines have been critical to help save lives and return the world to some normalcy over the past year.”
“Our expert review shows that the AstraZeneca COVID-19 vaccine and available mRNA vaccines provide similar, high-level protection against life-threatening COVID-19. This is important information for policy makers as they consider the optimal deployment of COVID-19 vaccines in their populations over the next 12 months,” says Professor Guy.
“Real-world data offer crucial insights into the effectiveness of vaccines, including the AstraZeneca COVID-19 vaccine. We are pleased that these data continue to show high-levels of protection against severe clinical outcomes and further our understanding of the important role that vaccination plays in the containment of COVID-19,” said John L. Perez, Senior Vice President, Head of Late Development Vaccines & Immune Therapies Unit, AstraZeneca.
AstraZeneca and its global partners have released over three billion vaccine doses to more than 180 countries, and approximately two-thirds of these doses have been delivered to lowand lower-middle income countries.
Based on model outcomes the AstraZeneca COVID-19 vaccine is estimated to have helped save over 6 million lives between 08 December 2020 and 08 December 2021.